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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4a3e4901ddc1ed8ba78659de2e4093d5f4b44651b0588c61e5e740f0fb9b75' 
  AND token = 'XS1E3FNoVqx+QP+Hxo7pbc+74jGk7ja4bJ+hN47YKV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}