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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89d4d1688f3573a80f6318df87a0e234ee9f3dab290c9616205bbdd8c05ba3d9' 
  AND token = 'iymqXTMP7KK1Hrb5em1V+ISD4k9lRbk0WHC67KIuBCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}