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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a4c45c843a118daed91d11ec17f1f08072bef52b1eea35edf6ad67d07f167d3' 
  AND token = 'M5gfJC6S0Hgfa0wy+lOGz4MAGIMQSvW+lm7k4KorQkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}