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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5486d4673928be77e6780b2b5e90cada0c851ce037d86a7c84b61aee046166b2' 
  AND token = '+YwimtdCf/2fOqdU6CMa140Un6hu6irvwcNCh6co3kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}