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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '115dd5bf428894e279471c49c4a2e2eb9e5001ae62fdb0a8b0379f5d1412e5c1' 
  AND token = '4d5chPe3MG2CvlLHQmrTYDFZJXir2FfvGTTHj75Z4GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}