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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66834b0988efcd2b62d8f2ac62963764228867edb5015e7c49c42d2296349196' 
  AND token = 'K4ynd/8hC1UHSsDHV4Bm1VRUI6SJyzTNo06AGioDT80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}