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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9851cd362108a9a135e5cbf7a12f4fddf885b78a9bc5af1f3f51580d120a7498' 
  AND token = '/LFwX0P0Hm9Lx9cjGonBXu9ijBaI7ag4EEwW0fdgGwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}