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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af41a850fe9161b4814a06fe24927d4f68e00b15b94c6fcaf204d819a102514c' 
  AND token = 'Mq0j6afI84YE+8L91UBS+VAXYYGaw8A1RW53c2Ca91E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}