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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd18108dc4c78da4d21f1dcc4751135b3a0215778a9509543dd86da348a5eb1c6' 
  AND token = 'RZiyFceWL/XsmtU+vtaM7FOGuF7HbyBtfQeqp6q4siA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}