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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed02f636480f5b725edb69ab71c3370bf2f1d1d1ec0af76f1a6b44a38594993a' 
  AND token = 'B7e4UvUSGjRyfWkTqS5TdwXT9pQZaOL9Dd3ZSeE4RGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}