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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b35a544a6ee07fbdf0a94bb41c5973aef67d1d30e65734023673349248452b41' 
  AND token = '1SRUvNUKoSa7FTvZpjH7c4yPM6HcCNQeCI/dp9G4alg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}