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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b46ea22cf4293491d718f01d73f0a237baccb548a42fd1bffa9be0367e8ad743' 
  AND token = 'R4vodkMipHNpTUUdL5jGm5mOxWjh9fjN3t22OsMRJb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}