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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db1cda4664c4588d4769dc90d0b1c9fdf3dc4f46263e7d639f957faedceeea9f' 
  AND token = 'mCtXlEym25ZWvYCaW+YfsVlLNMFZbRgzk9fLHRnOfnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}