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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c3879b1e1db15d803c8dbcc73f1abcb6bf2bd69e3221fb308cd58f9d40bfed0' 
  AND token = 'S1imfbYlRINszIpvvSYj6MNw14gnw79Kvz74Ju9SK8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}