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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75da1364bbe858770682f11a4fcb8218925a76954e3986f53baccafe5e255ab2' 
  AND token = '5TQYGrx+3ayX+VCH5s9pM2oLg/CZ2Of9pFGwN0Yk5ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}