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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15af4b7c2f4a784077ea1449a0b1d1b6b2ce40c4b204853715dde4f4b747ee31' 
  AND token = 'RsbHI4hXd6wHBRW01FcWWwmlR75dMUBx3WDOPAK7ZhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}