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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40d75b500666d876caf4e8aaf12f4579f73dcf9600f3df3a4d69793211ec5c95' 
  AND token = 'PYQJ4HRDCCgD2g1g/WTyf2yl214AEbllYkikSY3Jvck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}