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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e3cf672088153e5fb16020c25bcbd9b2b4a8b1f9c370d193f30b89a7c6be1f' 
  AND token = '0sVYb41EVyYsjq7MzmkZjEif4VhRG/Mnksqj21eiB70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}