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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2eb0bcc8854a025346d860e08b5d1dc7b245f7a97405f48c7135a5e9508aa3' 
  AND token = 'Xe5faaCZeWRv1xxsbx9hBF5vS1OP32+0Bv3dtSdb80c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}