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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '617021e107d1a620aaf1fc18a2608aa1af4ba55092dede1da6ba9f70992324ee' 
  AND token = 'lLCW0iM6ayuaTDCiSmPEUFxTZtA4q6DmSK65vPW8yzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}