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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c7d23f053dd18195e1d41a74af1351f37b9c3c8c62828b42a9d4073bf1d3b1' 
  AND token = 'ARGpNTbPNg8iWmSbAem0+PXSOn5OdSos0Z4t35+NZg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}