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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3225e6578056e5a2362afb89d6f7198674342fb188db0678ffe8b3fd136ca291' 
  AND token = '7RTZyFG/w4Le0P9lQN4fL+pWwN70n028x/jyn+OHZ+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}