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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '226a7170466ac158af1d4a540232072a607c3225bdbff9ab440c3509814cdb4a' 
  AND token = 'qAp5s7W6it2X1iPMcx86+gOY7h3g/ecimt0kmHQI+MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}