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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ccf2bb81024a43d8aecc75815bde638d2097169c1cf6d3a14b27a569d8a11ff' 
  AND token = 'vAMc5w4VAkP0Cg0vT0WKSVJigRWY8zOTC5qXIPbF78Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}