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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '959aa5416968af2c17fc2bfba306b83f1b191c123cf7167067b615ed7278a171' 
  AND token = '8d7a5X7mhWexoA7g7/QqxNdinIIcfxpAVWG6HZ+/LT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}