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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdb48680f6f29767b2d2bb460cb2fa64a3bb21a08ab15a9b7c18b5123a682731' 
  AND token = 'xDC3Bq1U+3pD1m1427BM3WjZI+/7blrx0Xhex9wO74w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}