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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8cb11cedf1ff9dfb3ad37781141afdcfa1549db2b73f35e13a456f274a1d0f8' 
  AND token = 'yaGX0Wj5V0rrEDaUJibiUfIlWK6ox3erYF2Kl1VP/g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}