SELECT 
  * 
FROM 
  cscart_settings_sections 
WHERE 
  name = 'Thumbnails' 
  AND type = 'CORE' 
  AND (
    FIND_IN_SET(
      'STOREFRONT', cscart_settings_sections.edition_type
    ) 
    OR FIND_IN_SET(
      'VENDOR', cscart_settings_sections.edition_type
    ) 
    OR FIND_IN_SET(
      'ROOT', cscart_settings_sections.edition_type
    ) 
    OR FIND_IN_SET(
      'ULT:STOREFRONT', cscart_settings_sections.edition_type
    ) 
    OR FIND_IN_SET(
      'ULT:VENDOR', cscart_settings_sections.edition_type
    ) 
    OR FIND_IN_SET(
      'ULT:ROOT', cscart_settings_sections.edition_type
    )
  )

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "23.86"
    },
    "table": {
      "table_name": "cscart_settings_sections",
      "access_type": "ALL",
      "rows_examined_per_scan": 106,
      "rows_produced_per_join": 2,
      "filtered": "2.50",
      "cost_info": {
        "read_cost": "23.33",
        "eval_cost": "0.53",
        "prefix_cost": "23.86",
        "data_read_per_join": "1K"
      },
      "used_columns": [
        "section_id",
        "parent_id",
        "edition_type",
        "name",
        "position",
        "type"
      ],
      "attached_condition": "((`atulecarter_atul_demo5`.`cscart_settings_sections`.`name` = 'Thumbnails') and (`atulecarter_atul_demo5`.`cscart_settings_sections`.`type` = 'CORE') and (find_in_set('STOREFRONT',`atulecarter_atul_demo5`.`cscart_settings_sections`.`edition_type`) or find_in_set('VENDOR',`atulecarter_atul_demo5`.`cscart_settings_sections`.`edition_type`) or find_in_set('ROOT',`atulecarter_atul_demo5`.`cscart_settings_sections`.`edition_type`) or find_in_set('ULT:STOREFRONT',`atulecarter_atul_demo5`.`cscart_settings_sections`.`edition_type`) or find_in_set('ULT:VENDOR',`atulecarter_atul_demo5`.`cscart_settings_sections`.`edition_type`) or find_in_set('ULT:ROOT',`atulecarter_atul_demo5`.`cscart_settings_sections`.`edition_type`)))"
    }
  }
}