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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '259ddba3fb268f2a6afb48be79cbc17c2e7734a02652e8c7dc47df5752a9e08b' 
  AND token = 'zsMSU1WBqDS0eOoEKVSkX5PrzBru2VNj/UC4Rqqm1Ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}