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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6323386b24f5d86db53cab04fad7acf628b2cf1c8ba054567396868bb7c65737' 
  AND token = 'gzq7XMPwZ98qU8DJ9Mn2krig9In1kxL0kqYT53MBwk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}