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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16ae35fad0f07499a09c60d078dc0cf99591dc9e3f632455e8a999ca9718591' 
  AND token = 'IEUsQ+QbLq/0CnC0bfbB+gblLtlyld+km4DP+FnELek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}