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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df0413c5cce28da466f661ac7c547daac7be31356eddcdbbde85a008fabecf71' 
  AND token = 'XdjsgzyWkSP07rcd9yTBA7Hpn9fVsZqyN1FXoqBhZzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}