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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e89cd7490d3da8ec8eac0ed05278d57c7daa0efe90f5b84cc81617131183d2a' 
  AND token = '+oGwDs2a0r1AeYdD8pQJxV7fKLQt1FjUELJOxdZiDd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}