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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '073f7c11f5f555fc6b542ac3809b79dd61e2fc5ad7dd1e9ee6a81eedbec133b1' 
  AND token = 'MF35ralI1sxF84InEyjoIjdjOAVZ6yYHIKzICDYDPeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}