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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1b0e1d5fae372079121ac68f94ecfda41c9511ee5b778d269ed743d83fd455' 
  AND token = 'ZcTuA/HYgfl/XwTFav7AWxN1rtghMYxU44I4ZwMVhZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}