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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '536673d95d6d82c80a212168171d711c3c20f69be3d15f55152e6df9f998d2f4' 
  AND token = 'uKUO+eBffK2rj5k7yekcRqU36Fhwxi9gZY2eEUREsgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}