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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f3e47317f172acabe0a90b79da05e94f6c49081075459b9d96f10cd08f9827' 
  AND token = '/BnXHtxmjGcXmYIsVfszjr1sc4ce0RMZSuxAbopdcYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}