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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41446194116b0a696bcb64d06d4bc96f3801b1e3c14907019f12b2297ea17060' 
  AND token = 'iQIG58p49FoWxm3MKGblJ1lnvkYn7xdmP4xB0L0Y2wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}