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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '126ebd706e458ca212952ce1291584e22e6468d3ab3b64ba6f64d5f7214c05c4' 
  AND token = 'NUa/NIOTQO7I0CqWCjR+7gXxx2YqpzTYqHsk0KH4g68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}