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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8be9d455f1360ea8cd5da88af183cfdf1126219f7475c29451006fcc72edc4dc' 
  AND token = 'PMhK8Uzsv4fq/R9UwOniS7fo1FALUvaVa/R5oB+usMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}