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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51041efab843637bf84cc823b26c2d82ebd74283b13b31e372670d495be4c50a' 
  AND token = 'BUon9uevJH3xnB9lCI0rdfylX7CivnYBct5KqP5KSMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}