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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3251a273032fe0ff643efee1b87ad01488945fd305512e43cba49dc0812c2c8' 
  AND token = 'mIR+rUjL2J2sMxztBh1KNooLndGKhfmIYnk3yN2qj60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}