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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c633256d359bdc4c00ff1e7e2c524cbf2caf6ec864dc499e82c4af9c9a677b2b' 
  AND token = 'm8uXDsx83DJCH3/Xsgmlf1Nho2cG/LYukVIeFvPgye4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}