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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fada96193069c2ea909d61fd9c606d31076ec4d8abc23359126ccf95d9e0514' 
  AND token = 'bt3g6TOAPPA1Xfx2ADBXhQKzSH1rHsGvBppBsvdvgV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}