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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a84e73f7a064a095becae3ed53091b7ecc9637839ee9671688a27eb30873c28e' 
  AND token = '+MeEwyiakU2sDwRO3a0UjxEE5P6RRzXn3BUGO5RHGns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}