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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb35b01f7bdc44137cce724daff51817e39011e5540cb8d58caccf88a72bf794' 
  AND token = 'kfrGFtlf/tdGo9IHR9WytICxe6C8NcQ4vEgtzXtXxQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}