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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d0fc0189d72482d4b9e2717eb3a09da487ece147f473b05f08a5a8487b134c2' 
  AND token = '50ov8hti+LIgV/vVvbfdfU8/B714iyk95y3hs6pQ/6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}