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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c215ffee69abd917c1977386f96220fe36e561de0c3ecd27d3b146c0150eb636' 
  AND token = '3DHEE+KTFeU2cmmKAcjrTy4s5c1qpPES/26JFSm04kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}