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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7655f9cdcb4534d3bdf88caab8163f8f41daf10e048c74337d2a226c462edc40' 
  AND token = '0PfuSclY0DwG6AUxtLjP3u0HY5R6A1qg7VCa86GbrKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}