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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f4f7fbedd0b6a297bdc8c971424f76ab8b4e0b525d5571388fea88caeea827f' 
  AND token = 'jQ/fMxQ8dyp7bDGQbluVgJuCdKglh5GB167eDXXyD7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}